Links
Database
Genomics
Transcriptomics & Proteomics
Organism-specific Database
Prokaryotes:
Plants & Fungi:
- SGD - Saccharomyces spp.
- CGD - Candida albicans
- TAIRS - Arabidopsis thaliana
- Granmene - several cereal plants
Invertebrates:
Mammals:
- MGI - Mus musculus
- RGD - Rattus norvegicus
Phylogeny & Taxonomy
- The Tree of Life
- Species 2000 - index of the world's known species
- TreeBASE - a database of phylogenetic knowledge
- MEGA - Molecular Evolutionary Genetics Analysis
- PAML - Phylogenetic Analysis by Maximum Likelihood
- PHYML - a phylogeny software based on the maximum-likelihood principle
- PHYLIP - package of programs for inferring phylogenies
- TreeView - user friendly tree displaying for Macs & Windows
Gene Expression Databases
Microarray analysis
- Gene Expression Omnibus (NCBI)
- ArrayExpress - is a public archive for transcriptomics data, which is aimed at storing MIAME- and MINSEQE- compliant data in accordance with MGED recommendations.
- Stanford Microarray Database
- MGED - an international organization of biologists, computer scientists, and data analysts that aims to facilitate biological and biomedical discovery through data integration.
Bioconductor - an open source and open development software project for the analysis and comprehension of genomic data.
Gene Regulation
- TRAFAC- For identifying conserved and shared cis regulatory elements between a pair of genes.
- CisMols - For identifying conserved and shared cis regulatory elements between a set of co-expressed genes.
- EPD - eukaryotic promoter database
- DBTSS - DataBase of Transcriptional Start Sites (human)
- SCPD - Saccharomyces cerevisiae promoter database
- DCPD - Drosophila Core Promoter Database
- RegulonDB - a database on transcriptional regulation in E. coli
- DPInteract - protein binding sites on E. coli DNA
- PromoterInspector - prediction of promoter regions in mammalian genomic sequences
- MatInspector - search for transcription factor binding sites
- Cister - cis-element cluster finder
- Gene regulatory Tools
Bioinformatics on-line course materials and tutorials
Human Diseases and Cancer Databases
- OMIM - a comprehensive, authoritative compendium of human genes and genetic phenotypes that is freely available and updated daily.
- MalaCards - an integrated database of human maladies and their annotations,modeled on the architecture and richness of the popular GeneCards databse of human gene.
- TCGA - (The Cancer Genome Atlas) a collaboration between the National Cancer Institute(NIC) And the National Human Genome Research Institute (NHGRI)that has generated comprehensive,mutil-dimensional maps of the key genomic changes in 33 types of cancer.
- CCLE - (Cancer Cell Line Encycclopedia) a collaboration between the Board Institute,and the Novartis Institute for Biomedical Research and its Genomics Institute of the Novartis Research Foundation to conduct a detailed genetic and pharmacologic characterization of a large panel of human cancer models, to develop integrated computational analyses that link distinct pharmacologic vulnerabilities to genomic patters and to translate cell line integrative genomics into cancer patient stratiffication.The CCLE provides public access to genomic data,analysis and visualization for about 1000 cell lines.
- Cancer Genome Anatomy Project
- The Cancer Genome Atlas
- Cancer Genetics With an Edge
- Cancers Genomes and their Implications for Curing Cancer by Bert Vogelstein
- Cancer Risk Prediction Models and Assessment